Custom polyclonal antibody production can be achieved by making use of healthy and flexible immunization procedures. With the increasing competition in the industry, most science service providers are committed to providing users with several protocol packages at the most competitive prices. They also deliver their packages for immunization schedules for a variety of animal species, such as goats, rabbits, mice, etc., for creating custom polyclonal antibodies to protein and peptide antigens.
The process of Polyclonal antibody production involves a variety of steps, ranging from designing a peptide, synthesizing them, and the conjugation of carrier protein to animalimmune, collection of serum, analyzing titers, and antibody purification. Most science-serving companies provide their customers with comprehensive technical and customer support services for all of their customers’ polyclonal antibody production stages.
These service providers will be specializing in antigen design and production of the custom peptide as well as monospecific peptide antibodies to discrete epitopes. They will also be capable of immunizing with recombinant proteins or protein pieces provided by their customers or expressed and sanitized by them to produce antibodies in a range of animal species, including rabbits, goats, chickens, mice, guinea pigs, as well as rats.
The process of Polyclonal antibody production also involves stimulating the animal body using antigens and generating an immunological response. It entails the binding of a group of immunoglobulins, which are specifically for antigens. They are then manufactured and exuded by the plasma cells of the body. The production process involves the use of different antibodies.
Polyclonal antibodies are one of the two commonly used antibodies, the other type of antibodies are the monoclonal antibodies. Polyclonal antibodies are produced through the use of numerous B lymphocyte clones, stimulated by multiple antigenic determinants, and can bind to multiple antigenic epitopes. The general production process of polyclonal antibodies usually consists of a range of steps, including:
- Preparing an antigen for the production process
- Immunization of the host animals
- Testing the potency
- Releasing the final product
- Antibody similarity sanitization
- Strengthening the produced antibodies
- Preserving the manufactured antibodies
Above all, the process of polyclonal antibody production needs the relevant resources to produce antibodies with matchless specificity, similarity, and assay usefulness.