Similar to Freund’s complete Adjuvant, Incomplete Freund’s Adjuvant and Freund’s Incomplete Adjuvant are also immunity boosters, which are typically employed to amplify the immune response of the animal recipient. These adjuvants are the original form of adjuvants, as well, which are incorporated with a mixture of mineral oil and water. The Incomplete Freund’s Adjuvant and Freund’s Incomplete Adjuvant chiefly differ from their complete versions in the nonattendance of the heat-murdered Mycobacterium genus. It means that the Incomplete Freund’s Adjuvant and Freund’s Incomplete Adjuvant do not comprise the mycobacterial components that are destroyed through heat.
As Incomplete Freund’s Adjuvant and Freund’s Incomplete Adjuvant consist of an emulsion of mineral oil and water, they improve the immune response in the animal hosts.
Incomplete Freund’s Adjuvant and Freund’s Incomplete Adjuvant occupy an important position in perking up the immune response against antigens.
Like Freund’s Complete Adjuvants, which are incorporated with heat-shattered Mycobacterium tuberculosis in a mixture of nonmetabolizable oils and water, Incomplete Freund’s Adjuvant and Freund’s Incomplete Adjuvant do not comprise any heat-destroyed Mycobacterium class.
Unlike Freund’s complete Adjuvants that stimulate the production of animal body Th1 cells, Incomplete Freund’s Adjuvant and Freund’s Incomplete Adjuvant are capable of arousing the manufacture of animal body Th2 cells.
In order to enhance the immune effect, Freund’s incomplete adjuvant is generally used for the second immunization of animals, only after the first immunization of Freund’s complete adjuvant is successful.